{"data":{"id":"us-sc/s.c.-code-ann.-44-53-190","jurisdiction":"us-sc","citation":"S.C. Code Ann. § 44-53-190","heading":"Schedule I.","body":"(A) The controlled substances listed in this section are included in Schedule I.\n(B) Any of the following opiates, including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, unless specifically excepted, whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation:\n1. Acetylmethadol\n2. Allylprodine\n3. Alphacetylmethadol\n4. Alphameprodine\n5. Alphamethadol\n6. Benzethidine\n7. Betacetylmethadol\n8. Betameprodine\n9. Betamethadol\n10. Betaprodine\n11. Clonitazene\n12. Dextromoramide\n13. [Deleted]\n14. Diampromide\n15. Diethylthiambutene\n16. Dimenoxadol\n17. Dimepheptanol\n18. Dimethylthiambutene\n19. Dioxaphetyl butyrate\n20. Dipipanone\n21. Ethylmethylthiambutene\n22. Etonitazene\n23. Etoxeridine\n24. Furethidine\n25. Hydroxypethidine\n26. Ketobemidone\n27. Levomoramide\n28. Levophenacylmorphan\n29. Morpheridine\n30. Noracymethadol\n31. Norlevorphanol\n32. Normethadone\n33. Norpipanone\n34. Phenadoxone\n35. Phenampromide\n36. Phenomorphan\n37. Phenoperidine\n38. Piritramide\n39. Proheptazine\n40. Properidine\n41. Racemoramide\n42. Trimeperidine\n43. Propiram\n44. Difenoxin\n45. Alfentanyl\n46. Tilidine\n47. Alphamethylfentanyl (N-[1-(alpha-methyl-beta-phenyl) ethyl-4-piperidyl] propionanilide; 1-(1-methyl-2-phenylethyl-4-(N-pro-panilido) piperidine).\n48. Fentanyl-related substances. Unless specifically excepted, listed in another schedule, or contained within a pharmaceutical product approved by the United States Food and Drug Administration, any material, compound, mixture, or preparation, including its salts, isomers, esters, or ethers, and salts of isomers, esters, or ethers, that is structurally related to fentanyl by one or more of the following modifications:\n(a) replacement of the phenyl portion of the phenethyl group by any monocycle, whether or not further substituted in or on the monocycle;\n(b) substitution in or on the phenethyl group with alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino or nitro groups;\n(c) substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, amino or nitro groups;\n(d) replacement of the aniline ring with any aromatic monocycle whether or not further substituted in or on the aromatic monocycle; or\n(e) replacement of the N propionyl group by another acyl group or hydrogen.\nThis definition includes, but is not limited to, the following substances: Methylacetyl fentanyl, Alpha methylfentanyl, Methylthiofentanyl, Benzylfentanyl, Beta hydroxyfentanyl, Beta hydroxy 3 methylfentanyl, 3 Methylfentanyl, Methylthiofentanyl, Fluorofentanyl, Thenylfentanyl or Thienyl fentanyl, Thiofentanyl, Acetylfentanyl, Butyrylfentanyl, Beta Hydroxythiofentanyl, Lofentanil, Ocfentanil, Ohmfentanyl, Benzodioxolefentanyl, Furanyl fentanyl, Pentanoyl fentanyl, Cyclopentyl fentanyl, Isobutyryl fentanyl, Remifentanil, Crotonyl fentanyl, Cyclopropyl fentanyl, Valeryl fentanyl, Fluorobutyryl fentanyl, Fluoroisobutyryl fentanyl, Methoxybutyryl fentanyl, Isobutyryl fentanyl, Chloroisobutyryl fentanyl, Acryl fentanyl, Tetrahydrofuran fentanyl, Methoxyacetyl fentanyl, Fluorocrotonyl fentanyl, Cyclopentenyl fentanyl, Phenyl fentanyl, Cyclobutyl fentanyl, Methylcyclopropyl fentanyl.\n(C) Any of the following opium derivatives, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:\n1. Acetorphine\n2. Acetyldihydrocodeine\n3. Benzylmorphine\n4. Codeine methylbromide\n5. Codeine-N-Oxide\n6. Cyprenorphine\n7. Desomorphine\n8. Dihydromorphine\n9. Etorphine\n10. Heroin\n11. Hydromorphinol\n12. Methyldesorphine\n13. Methylhydromorphine\n14. Morphine methylbromide\n15. Morphine methylsulfonate\n16. Morphine-N-Oxide\n17. Myrophine\n18. Nicocodeine\n19. Nicomorphine\n20. Normorphine\n21. Pholcodine\n22. Thebacon\n23. Drotebanol\n(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:\n1. 3,4-methylenedioxy amphetamine\n2. 5-methoxy-3,4-methylenedioxy amphetamine\n3. 3,4-methylenedioxymethamphetamine (MDMA)\n4. 3,4,5-trimethoxy amphetamine\n5. Bufotenine\n6. Diethyltryptamine (DET)\n7. Dimethyltryptamine (DMT)\n8. 4-methyl-2,5-dimethoxyamphetamine (STP)\n9. Ibogaine\n10. Lysergic acid diethylamide (LSD)\n11. Marijuana\n12. Mescaline\n13. Peyote\n14. N-ethyl-3-piperidyl benzilate\n15. N-methyl-3-piperidyl benzilate\n16. Psilocybin\n17. Psilocyn\n18. Tetrahydrocannabinol (THC)\n19. 2,5-dimethoxyamphetamine\n20. 4-bromo-2,5-dimethoxyamphetamine\n21. 4-Methoxyamphetamine\n22. Thiophene analog of phencyclidine\n23. Parahexyl\n24. Synthetic cannabinoids.—Any material, compound, mixture, or preparation that is not listed as a controlled substance in Schedule I through V, is not an FDA-approved drug, and contains any quantity of the following substances, their salts, isomers (whether optical, positional, or geometric), homologues, and salts of isomers and homologues, unless specifically excepted, whenever the existence of these salts, isomers, homologues, and salts of isomers and homologues is possible within the specific chemical designation:\na. Naphthoylindoles. Any compound containing a 3-(1-naphthoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-015, JWH-018, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, JWH-210, JWH-398, AM-2201, WIN 55-212, AM-2201 (C1 analog), AM-1220.\nb. Naphthylmethylindoles. Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.\nc. Naphthoylpyrroles. Any compound containing a 3-(1-naphthoyl)pyrrole structure with substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-307, JWH-370, JWH-176.\nd. Naphthylmethylindenes. Any compound containing a naphthylideneindene structure with substitution at the 3-position of the indene ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.\ne. Phenylacetylindoles. Any compound containing a 3-phenylacetylindole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, SR-18, RCS-8, JWH-203, JWH-250, JWH-251.\nf. Cyclohexylphenols. Any compound containing a 2-(3-hydroxycyclohexyl)phenol structure with substitution at the 5-position of the phenolic ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not substituted in the cyclohexyl ring to any extent. Including, but not limited to, CP 47,497 (and homologues), cannabicyclohexanol, CP-55, 940.\ng. Benzoylindoles. Any compound containing a 3-(benzoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, AM-694, Pravadoline (WIN 48,098), RCS-4, AM-630, AM-1241, AM-2233.\nh. 2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo [1,2,3-de]-1, 4-benzoxazin-6-yl]-1-napthalenylmethanone (WIN 55,212-2).\ni. 9-(hydroxymethyl)-6,6-dimethy l-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol 7370 (HU-210, HU-211).\nj. Adamantoylindoles. Any compound containing a 3-(1-adamantoyl)indole structure with substitution at the nitrogen atom of the indole ring by a alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring system to any extent.\n(E) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substance having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers if possible within the specific chemical designation:\n(1) Mecloqualone;\n(2) Methaqualone; or\n(3) Gamma Hydroxybutyric Acid.\n(F) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers, and salts of isomers:\n(1) Fenethylline;\n(2) N-ethylamphetamine;\n(3) Cathinone; or\n(4) Substituted Cathinones.\nAny compound (not being bupropion) structurally derived from 2-amino-1-phenyl-1-propanone by modification in any of the following ways:\n(a) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;\n(b) by substitution at the 3-position with an alkyl substituent;\n(c) by substitution at the nitrogen atom with alkyl or dialkyl groups, benzyl or methoxybenzyl groups; or\n(d) by inclusion of the nitrogen atom in a cyclic structure.\nIncluding, but not limited to: Methylone, Mephedrone, 3,4-Methylenedioxypyrovalerone (MDPV), Butylone, Methedrone, 4-Methylethcathinone, Flephedrone, Pentylone, Pentedrone, Buphedrone.","path":["Title 44 - HEALTH","CHAPTER 53 Poisons, Drugs, and Other Controlled Substances","ARTICLE 3 Narcotics and Controlled Substances"],"source_url":"https://www.scstatehouse.gov/code/t44c053.php","current_through":"2025 Session of the General Assembly","vintage":"","retrieved_at":"2026-09-02T07:33:34Z","sha256":"76f7752a4094175b2b6d26d62ca6bfa4e474574f9538194bbc310bd1893e5b21","source_id":"us-sc","stale":false,"prev":"us-sc/s.c.-code-ann.-44-53-180","next":"us-sc/s.c.-code-ann.-44-53-200"},"notice":"GroundRules: Original legal text. Not legal advice."}