{"data":{"id":"us/21-cfr-170.245","jurisdiction":"us","citation":"21 CFR 170.245","heading":"Part 5 of a GRAS notice: Experience based on common use in food before 1958.","body":"If the statutory basis for your conclusion of GRAS status is through experience based on common use in food, in Part 5 of your GRAS notice you must include evidence of a substantial history of consumption of the notified substance for food use by a significant number of consumers prior to January 1, 1958.","path":["Title 21—Food and Drugs","CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES","SUBCHAPTER B—FOOD FOR HUMAN CONSUMPTION","PART 170—FOOD ADDITIVES","Subpart E—Generally Recognized as Safe (GRAS) Notice"],"source_url":"https://www.ecfr.gov/api/versioner/v1/full/2026-08-25/title-21.xml","current_through":"2026-08-25","vintage":"","retrieved_at":"2026-08-27T02:24:47Z","sha256":"b15663e6a6eeffa585af28a941e63322c0e42ca6d1ab8f5831fe565770a528da","source_id":"us-cfr","stale":true,"prev":"us/21-cfr-170.240","next":"us/21-cfr-170.250"},"notice":"GroundRules: Original legal text. Not legal advice."}