{"data":{"id":"us/21-cfr-343.12","jurisdiction":"us","citation":"21 CFR 343.12","heading":"Cardiovascular active ingredients.","body":"(a) Aspirin.\n(b) Buffered aspirin. Aspirin identified in paragraph (a) of this section may be buffered with any antacid ingredient(s) identified in § 331.11 of this chapter provided that the finished product contains at least 1.9 milliequivalents of acid-neutralizing capacity per 325 milligrams of aspirin as measured by the procedure provided in the United States Pharmacopeia 23/National Formulary 18.","path":["Title 21—Food and Drugs","CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES","SUBCHAPTER D—DRUGS FOR HUMAN USE","PART 343—INTERNAL ANALGESIC, ANTIPYRETIC, AND ANTIRHEUMATIC DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE","Subpart B—Active Ingredients"],"source_url":"https://www.ecfr.gov/api/versioner/v1/full/2026-08-25/title-21.xml","current_through":"2026-08-25","vintage":"","retrieved_at":"2026-08-27T02:24:47Z","sha256":"ebf54ec92c4cc7eeaf7e475d4608cfb1fdf18d6686eb0d1536ecb3a469e7752b","source_id":"us-cfr","stale":true,"prev":"us/21-cfr-343.10","next":"us/21-cfr-343.13"},"notice":"GroundRules: Original legal text. Not legal advice."}