{"data":{"id":"us/42-cfr-419.49","jurisdiction":"us","citation":"42 CFR 419.49","heading":"Additional payment for technetium-99m (Tc-99m) derived from domestically produced molybdenum-99 (Mo-99).","body":"(a) General rule. CMS provides for an additional payment beyond the standard payment to a hospital for a dose of Tc-99m derived from Mo-99, if at least 50 percent of the Mo-99 in the Tc-99m generator that produced the dose was both irradiated and processed in the United States.\n(1) Domestically produced Mo-99 refers to Mo-99 that was both irradiated and processed in the United States.\n(2) Irradiated refers to the process of bombarding a uranium or molybdenum target with radiation in order to produce Mo-99. Irradiation is typically performed with a nuclear reactor or particle accelerator.\n(3) Processed refers to the purification of Mo-99 from irradiated material.\n(b) Exclusions. A dose of Tc-99m does not qualify for the add-on payment if more than 50 percent of the Mo-99 in the Tc-99m generator was irradiated or processed outside the United States, even if the Mo-99 has been loaded into a Tc-99m generator in the United States or if the Tc-99m has been eluted at a radiopharmacy in the United States.\n(1) Eluted refers to the process by which Tc-99m is chemically separated from Mo-99 within the generator and collected in an elution vial.\n(2) [Reserved]","path":["Title 42—Public Health","CHAPTER IV—CENTERS FOR MEDICARE \u0026 MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES","SUBCHAPTER B—MEDICARE PROGRAM","PART 419—PROSPECTIVE PAYMENT SYSTEMS FOR HOSPITAL OUTPATIENT DEPARTMENT SERVICES","Subpart D—Payments to Hospitals"],"source_url":"https://www.ecfr.gov/api/versioner/v1/full/2026-08-25/title-42.xml","current_through":"2026-08-25","vintage":"","retrieved_at":"2026-08-27T02:26:11Z","sha256":"a6dcab1baacddced94a511a765acf381c57956f75354c0da7733027129cfe3e2","source_id":"us-cfr","stale":true,"prev":"us/42-cfr-419.48","next":"us/42-cfr-419.50"},"notice":"GroundRules: Original legal text. Not legal advice."}