Federal regulations · Through 2026-08-25 · Newer source version available

21 CFR 558.248: Erythromycin.

(a) Specifications. Type A medicated articles containing 92.5 grams per pound erythromycin (as the thiocyanate salt).
(b) Sponsor. See No. 061133 in § 510.600(c) of this chapter.
(c) Related tolerances. See § 556.230 of this chapter.
(d) Special considerations. (1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
(2) The expiration date of VFDs for erythromycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for erythromycin shall not be refilled.
(e) Conditions of use—(1) Chickens—
Erythromycin in grams/ton Combination in grams/ton Indications for use Limitations Sponsor
(i) 92.5 Chickens: As an aid in the prevention of chronic respiratory disease during periods of stress Feed for 2 days before stress and 3 to 6 days after stress. Withdraw 24 hours before slaughter 061623
(ii) 92.5 Chickens: As an aid in the prevention of infectious coryza Feed for 7 to 14 days. Withdraw 24 hours before slaughter 061623
(iii) 185 Chickens: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD) Feed for 5 to 8 days. Withdraw 48 hours before slaughter. Do not use in birds producing eggs for food 061623
(2) Turkeys—
Erythromycin thiocyanate in grams/ton Combination in grams/ton Indications for use Limitations Sponsor
(i) 92.5 Turkeys: As an aid in the prevention of chronic respiratory disease during periods of stress Feed for 2 days before stress and 3 to 6 days after stress 061623
(ii) 185 Turkeys: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD) Feed for 5 to 8 days. Do not use in birds producing eggs for food 061623

Where this section sits in the code

Title 21—Food and Drugs
CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES
SUBCHAPTER E—ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS
PART 558—NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS
Subpart B—Specific New Animal Drugs for Use in Animal Feeds

(a) Specifications. Type A medicated articles containing 92.5 grams per pound erythromycin (as the thiocyanate salt).

(b) Sponsor. See No. 061133 in § 510.600(c) of this chapter.

(d) Special considerations. (1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.

(2) The expiration date of VFDs for erythromycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for erythromycin shall not be refilled.

(e) Conditions of use—(1) Chickens—

Erythromycin in grams/ton Combination in grams/ton Indications for use Limitations Sponsor

(i) 92.5 Chickens: As an aid in the prevention of chronic respiratory disease during periods of stress Feed for 2 days before stress and 3 to 6 days after stress. Withdraw 24 hours before slaughter 061623

(ii) 92.5 Chickens: As an aid in the prevention of infectious coryza Feed for 7 to 14 days. Withdraw 24 hours before slaughter 061623

(iii) 185 Chickens: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD) Feed for 5 to 8 days. Withdraw 48 hours before slaughter. Do not use in birds producing eggs for food 061623

(2) Turkeys—

Erythromycin thiocyanate in grams/ton Combination in grams/ton Indications for use Limitations Sponsor

(i) 92.5 Turkeys: As an aid in the prevention of chronic respiratory disease during periods of stress Feed for 2 days before stress and 3 to 6 days after stress 061623

(ii) 185 Turkeys: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD) Feed for 5 to 8 days. Do not use in birds producing eggs for food 061623

Collected 2026-08-27T02:24:47Z. Source file · JSON

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