GroundRules
← Search the law
Federal regulations · Through 2026-08-25 · Newer source version available

40 CFR Appendix A to Part 355: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities

Read at publisher ↗
Where this section sits in the code
  1. Title 40—Protection of Environment
  2. CHAPTER I—ENVIRONMENTAL PROTECTION AGENCY
  3. SUBCHAPTER J—SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS
  4. PART 355—EMERGENCY PLANNING AND NOTIFICATION

[Alphabetical Order]

CAS No. Chemical name Notes Reportable quantity * (pounds) Threshold planning quantity (pounds)

75-86-5 Acetone Cyanohydrin 10 1,000

1752-30-3 Acetone Thiosemicarbazide 1,000 1,000/10,000

107-02-8 Acrolein 1 500

79-06-1 Acrylamide f 5,000 1,000/10,000

107-13-1 Acrylonitrile f 100 10,000

814-68-6 Acrylyl Chloride d 100 100

111-69-3 Adiponitrile f 1,000 1,000

116-06-3 Aldicarb b 1 100/10,000

309-00-2 Aldrin 1 500/10,000

107-18-6 Allyl Alcohol 100 1,000

107-11-9 Allylamine 500 500

20859-73-8 Aluminum Phosphide a 100 500

54-62-6 Aminopterin 500 500/10,000

78-53-5 Amiton 500 500

3734-97-2 Amiton Oxalate 100 100/10,000

7664-41-7 Ammonia f 100 500

300-62-9 Amphetamine 1,000 1,000

62-53-3 Aniline f 5,000 1,000

88-05-1 Aniline, 2,4,6-Trimethyl- 500 500

7783-70-2 Antimony Pentafluoride 500 500

1397-94-0 Antimycin A b 1,000 1,000/10,000

86-88-4 ANTU 100 500/10,000

1303-28-2 Arsenic Pentoxide 1 100/10,000

1327-53-3 Arsenous Oxide d 1 100/10,000

7784-34-1 Arsenous Trichloride 1 500

7784-42-1 Arsine 100 100

2642-71-9 Azinphos-Ethyl 100 100/10,000

86-50-0 Azinphos-Methyl 1 10/10,000

98-87-3 Benzal Chloride 5,000 500

98-16-8 Benzenamine, 3-(Trifluoromethyl)- 500 500

100-14-1 Benzene, 1-(Chloromethyl)-4-Nitro- 500 500/10,000

98-05-5 Benzenearsonic Acid 10 10/10,000

3615-21-2 Benzimidazole, 4,5-Dichloro-2-(Trifluoromethyl)- c 500 500/10,000

98-07-7 Benzotrichloride 10 100

100-44-7 Benzyl Chloride 100 500

140-29-4 Benzyl Cyanide d 500 500

15271-41-7 Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Chloro-6-((((Methylamino)Carbonyl)Oxy)Imino)-, (1s-(1-alpha,2-beta,4-alpha,5-alpha,6E))- 500 500/10,000

534-07-6 Bis(Chloromethyl) Ketone 10 10/10,000

4044-65-9 Bitoscanate 500 500/10,000

10294-34-5 Boron Trichloride 500 500

7637-07-2 Boron Trifluoride 500 500

353-42-4 Boron Trifluoride Compound With Methyl Ether (1:1) 1,000 1,000

28772-56-7 Bromadiolone 100 100/10,000

7726-95-6 Bromine f 500 500

1306-19-0 Cadmium Oxide 100 100/10,000

2223-93-0 Cadmium Stearate b 1,000 1,000/10,000

7778-44-1 Calcium Arsenate 1 500/10,000

8001-35-2 Camphechlor 1 500/10,000

56-25-7 Cantharidin 100 100/10,000

51-83-2 Carbachol Chloride 500 500/10,000

26419-73-8 Carbamic Acid, Methyl-, O-(((2,4-Dimethyl-1, 3-Dithiolan-2-yl)Methylene)Amino)- 100 100/10,000

1563-66-2 Carbofuran 10 10/10,000

75-15-0 Carbon Disulfide f 100 10,000

786-19-6 Carbophenothion 500 500

57-74-9 Chlordane 1 1,000

470-90-6 Chlorfenvinfos 500 500

7782-50-5 Chlorine 10 100

24934-91-6 Chlormephos 500 500

999-81-5 Chlormequat Chloride d 100 100/10,000

79-11-8 Chloroacetic Acid 100 100/10,000

107-07-3 Chloroethanol 500 500

627-11-2 Chloroethyl Chloroformate 1,000 1,000

67-66-3 Chloroform f 10 10,000

542-88-1 Chloromethyl Ether d 10 100

107-30-2 Chloromethyl Methyl Ether b 10 100

3691-35-8 Chlorophacinone 100 100/10,000

1982-47-4 Chloroxuron 500 500/10,000

21923-23-9 Chlorthiophos d 500 500

10025-73-7 Chromic Chloride 1 1/10,000

62207-76-5 Cobalt, ((2,2′-(1,2-Ethanediylbis (Nitrilomethylidyne)) Bis(6-Fluorophenolato))(2-)-N,N′,O,O′)- 100 100/10,000

10210-68-1 Cobalt Carbonyl d 10 10/10,000

64-86-8 Colchicine d 10 10/10,000

56-72-4 Coumaphos 10 100/10,000

5836-29-3 Coumatetralyl 500 500/10,000

95-48-7 Cresol, o- 100 1,000/10,000

535-89-7 Crimidine 100 100/10,000

4170-30-3 Crotonaldehyde 100 1,000

123-73-9 Crotonaldehyde, (E)- 100 1,000

506-68-3 Cyanogen Bromide 1,000 500/10,000

506-78-5 Cyanogen Iodide 1,000 1,000/10,000

2636-26-2 Cyanophos 1,000 1,000

675-14-9 Cyanuric Fluoride 100 100

66-81-9 Cycloheximide 100 100/10,000

108-91-8 Cyclohexylamine f 10,000 10,000

17702-41-9 Decaborane(14) 500 500/10,000

8065-48-3 Demeton 500 500

919-86-8 Demeton-S-Methyl 500 500

10311-84-9 Dialifor 100 100/10,000

19287-45-7 Diborane 100 100

111-44-4 Dichloroethyl ether 10 10,000

149-74-6 Dichloromethylphenylsilane 1,000 1,000

62-73-7 Dichlorvos 10 1,000

141-66-2 Dicrotophos 100 100

1464-53-5 Diepoxybutane 10 500

814-49-3 Diethyl Chlorophosphate d 500 500

71-63-6 Digitoxin b 100 100/10,000

2238-07-5 Diglycidyl Ether 1,000 1,000

20830-75-5 Digoxin d 10 10/10,000

115-26-4 Dimefox 500 500

60-51-5 Dimethoate 10 500/10,000

2524-03-0 Dimethyl Phosphorochloridothioate 500 500

77-78-1 Dimethyl sulfate 100 500

75-78-5 Dimethyldichlorosilane d 500 500

57-14-7 Dimethylhydrazine 10 1,000

99-98-9 Dimethyl-p-Phenylenediamine 10 10/10,000

644-64-4 Dimetilan 1 500/10,000

534-52-1 Dinitrocresol 10 10/10,000

88-85-7 Dinoseb 1,000 100/10,000

1420-07-1 Dinoterb 500 500/10,000

78-34-2 Dioxathion 500 500

82-66-6 Diphacinone 10 10/10,000

152-16-9 Diphosphoramide, Octamethyl- 100 100

298-04-4 Disulfoton 1 500

514-73-8 Dithiazanine Iodide 500 500/10,000

541-53-7 Dithiobiuret 100 100/10,000

316-42-7 Emetine, Dihydrochloride d 1 1/10,000

115-29-7 Endosulfan 1 10/10,000

2778-04-3 Endothion 500 500/10,000

72-20-8 Endrin 1 500/10,000

106-89-8 Epichlorohydrin f 100 1,000

2104-64-5 EPN 100 100/10,000

50-14-6 Ergocalciferol b 1,000 1,000/10,000

379-79-3 Ergotamine Tartrate 500 500/10,000

1622-32-8 Ethanesulfonyl Chloride, 2-Chloro- 500 500

10140-87-1 Ethanol, 1,2-Dichloro-, Acetate 1,000 1,000

563-12-2 Ethion 10 1,000

13194-48-4 Ethoprophos 1,000 1,000

538-07-8 Ethylbis(2-Chloroethyl)Amine d 500 500

371-62-0 Ethylene Fluorohydrin b, d 10 10

75-21-8 Ethylene Oxide f 10 1,000

107-15-3 Ethylenediamine 5,000 10,000

151-56-4 Ethyleneimine 1 500

542-90-5 Ethylthiocyanate 10,000 10,000

22224-92-6 Fenamiphos 10 10/10,000

115-90-2 Fensulfothion d 500 500

4301-50-2 Fluenetil 100 100/10,000

7782-41-4 Fluorine e 10 500

640-19-7 Fluoroacetamide 100 100/10,000

144-49-0 Fluoroacetic Acid 10 10/10,000

359-06-8 Fluoroacetyl Chloride b 10 10

51-21-8 Fluorouracil 500 500/10,000

944-22-9 Fonofos 500 500

50-00-0 Formaldehyde f 100 500

107-16-4 Formaldehyde Cyanohydrin d 1,000 1,000

23422-53-9 Formetanate Hydrochloride d 100 500/10,000

2540-82-1 Formothion 100 100

17702-57-7 Formparanate 100 100/10,000

21548-32-3 Fosthietan 500 500

3878-19-1 Fuberidazole 100 100/10,000

110-00-9 Furan 100 500

13450-90-3 Gallium Trichloride 500 500/10,000

77-47-4 Hexachlorocyclopentadiene d 10 100

4835-11-4 Hexamethylenediamine, N,N′-Dibutyl- 500 500

302-01-2 Hydrazine 1 1,000

74-90-8 Hydrocyanic Acid 10 100

7647-01-0 Hydrogen Chloride (gas only) f 5,000 500

7664-39-3 Hydrogen Fluoride 100 100

7722-84-1 Hydrogen Peroxide (Conc >52%) f 1,000 1,000

7783-07-5 Hydrogen Selenide 10 10

7783-06-4 Hydrogen Sulfide f 100 500

123-31-9 Hydroquinone f 100 500/10,000

13463-40-6 Iron, Pentacarbonyl- 100 100

297-78-9 Isobenzan 100 100/10,000

78-82-0 Isobutyronitrile d 1,000 1,000

102-36-3 Isocyanic Acid, 3,4-Dichlorophenyl Ester 500 500/10,000

465-73-6 Isodrin 1 100/10,000

55-91-4 Isofluorphate b 100 100

4098-71-9 Isophorone Diisocyanate g 500 500

108-23-6 Isopropyl Chloroformate 1,000 1,000

119-38-0 Isopropylmethyl-pyrazolyl Dimethylcarbamate 100 500

78-97-7 Lactonitrile 1,000 1,000

21609-90-5 Leptophos 500 500/10,000

541-25-3 Lewisite b, d 10 10

58-89-9 Lindane 1 1,000/10,000

7580-67-8 Lithium Hydride a 100 100

109-77-3 Malononitrile 1,000 500/10,000

12108-13-3 Manganese, Tricarbonyl Methylcyclopentadienyl d 100 100

51-75-2 Mechlorethamine b 10 10

950-10-7 Mephosfolan 500 500

1600-27-7 Mercuric Acetate 500 500/10,000

7487-94-7 Mercuric Chloride 500 500/10,000

21908-53-2 Mercuric Oxide 500 500/10,000

10476-95-6 Methacrolein Diacetate 1,000 1,000

760-93-0 Methacrylic Anhydride 500 500

126-98-7 Methacrylonitrile d 1,000 500

920-46-7 Methacryloyl Chloride 100 100

30674-80-7 Methacryloyloxyethyl Isocyanate d 100 100

10265-92-6 Methamidophos 100 100/10,000

558-25-8 Methanesulfonyl Fluoride 1,000 1,000

950-37-8 Methidathion 500 500/10,000

2032-65-7 Methiocarb 10 500/10,000

16752-77-5 Methomyl d 100 500/10,000

151-38-2 Methoxyethylmercuric Acetate 500 500/10,000

80-63-7 Methyl 2-Chloroacrylate 500 500

74-83-9 Methyl Bromide f 1,000 1,000

79-22-1 Methyl Chloroformate d 1,000 500

60-34-4 Methyl Hydrazine 10 500

624-83-9 Methyl Isocyanate 10 500

556-61-6 Methyl Isothiocyanate a 500 500

74-93-1 Methyl Mercaptan f 100 500

3735-23-7 Methyl Phenkapton 500 500

676-97-1 Methyl Phosphonic Dichloride a 100 100

556-64-9 Methyl Thiocyanate 10,000 10,000

78-94-4 Methyl Vinyl Ketone 10 10

502-39-6 Methylmercuric Dicyanamide 500 500/10,000

75-79-6 Methyltrichlorosilane d 500 500

1129-41-5 Metolcarb 1,000 100/10,000

7786-34-7 Mevinphos 10 500

315-18-4 Mexacarbate d 1,000 500/10,000

50-07-7 Mitomycin C 10 500/10,000

6923-22-4 Monocrotophos 10 10/10,000

2763-96-4 Muscimol 1,000 500/10,000

505-60-2 Mustard Gas d 500 500

13463-39-3 Nickel Carbonyl 10 1

54-11-5 Nicotine b 100 100

65-30-5 Nicotine Sulfate 100 100/10,000

7697-37-2 Nitric Acid 1,000 1,000

10102-43-9 Nitric Oxide b 10 100

98-95-3 Nitrobenzene f 1,000 10,000

1122-60-7 Nitrocyclohexane 500 500

10102-44-0 Nitrogen Dioxide 10 100

62-75-9 Nitrosodimethylamine d 10 1,000

991-42-4 Norbormide 100 100/10,000

Organorhodium Complex (PMN-82-147) 10 10/10,000

630-60-4 Ouabain b 100 100/10,000

23135-22-0 Oxamyl 100 100/10,000

78-71-7 Oxetane, 3,3-Bis(Chloromethyl)- 500 500

2497-07-6 Oxydisulfoton d 500 500

10028-15-6 Ozone 100 100

1910-42-5 Paraquat Dichloride 10 10/10,000

2074-50-2 Paraquat Methosulfate 10 10/10,000

56-38-2 Parathion b 10 100

298-00-0 Parathion-Methyl b 100 100/10,000

12002-03-8 Paris Green 1 500/10,000

19624-22-7 Pentaborane 500 500

2570-26-5 Pentadecylamine 100 100/10,000

79-21-0 Peracetic Acid 500 500

594-42-3 Perchloromethylmercaptan 100 500

108-95-2 Phenol 1,000 500/10,000

4418-66-0 Phenol, 2,2′-Thiobis(4-Chloro-6-Methyl)- 100 100/10,000

64-00-6 Phenol, 3-(1-Methylethyl)-, Methylcarbamate 10 500/10,000

58-36-6 Phenoxarsine, 10,10′-Oxydi- 500 500/10,000

696-28-6 Phenyl Dichloroarsine d 1 500

59-88-1 Phenylhydrazine Hydrochloride 1,000 1,000/10,000

62-38-4 Phenylmercury Acetate 100 500/10,000

2097-19-0 Phenylsilatrane d 100 100/10,000

103-85-5 Phenylthiourea 100 100/10,000

298-02-2 Phorate 10 10

4104-14-7 Phosacetim 100 100/10,000

947-02-4 Phosfolan 100 100/10,000

75-44-5 Phosgene f 10 10

13171-21-6 Phosphamidon 100 100

7803-51-2 Phosphine 100 500

2703-13-1 Phosphonothioic Acid, Methyl-, O-Ethyl O-(4-(Methylthio) Phenyl) Ester 500 500

50782-69-9 Phosphonothioic Acid, Methyl-, S-(2-(Bis(1Methylethyl)Amino)Ethyl) O-Ethyl Ester 100 100

2665-30-7 Phosphonothioic Acid, Methyl-, O-(4-Nitrophenyl) O-Phenyl Ester 500 500

3254-63-5 Phosphoric Acid, Dimethyl 4-(Methylthio)Phenyl Ester 500 500

2587-90-8 Phosphorothioic Acid, O,O-Dimethyl-S-(2-Methylthio) Ethyl Ester b, c 500 500

7723-14-0 Phosphorus a, d 1 100

10025-87-3 Phosphorus Oxychloride 1,000 500

10026-13-8 Phosphorus Pentachloride a 500 500

7719-12-2 Phosphorus Trichloride 1,000 1,000

57-47-6 Physostigmine 100 100/10,000

57-64-7 Physostigmine, Salicylate (1:1) 100 100/10,000

124-87-8 Picrotoxin 500 500/10,000

110-89-4 Piperidine 1,000 1,000

23505-41-1 Pirimifos-Ethyl 1,000 1,000

10124-50-2 Potassium Arsenite 1 500/10,000

151-50-8 Potassium Cyanide a 10 100

506-61-6 Potassium Silver Cyanide a 1 500

2631-37-0 Promecarb d 1,000 500/10,000

106-96-7 Propargyl Bromide 10 10

57-57-8 Propiolactone, Beta- 10 500

107-12-0 Propionitrile 10 500

542-76-7 Propionitrile, 3-Chloro- 1,000 1,000

70-69-9 Propiophenone, 4-Amino- c 100 100/10,000

109-61-5 Propyl Chloroformate 500 500

75-56-9 Propylene Oxide f 100 10,000

75-55-8 Propyleneimine 1 10,000

2275-18-5 Prothoate 100 100/10,000

129-00-0 Pyrene b 5,000 1,000/10,000

140-76-1 Pyridine, 2-Methyl-5-Vinyl- 500 500

504-24-5 Pyridine, 4-Amino- d 1,000 500/10,000

1124-33-0 Pyridine, 4-Nitro-,l-Oxide 500 500/10,000

53558-25-1 Pyriminil d 100 100/10,000

14167-18-1 Salcomine 500 500/10,000

107-44-8 Sarin d 10 10

7783-00-8 Selenious Acid 10 1,000/10,000

7791-23-3 Selenium Oxychloride 500 500

563-41-7 Semicarbazide Hydrochloride 1,000 1,000/10,000

3037-72-7 Silane, (4-Aminobutyl)Diethoxymethyl- 1,000 1,000

7631-89-2 Sodium Arsenate 1 1,000/10,000

7784-46-5 Sodium Arsenite 1 500/10,000

26628-22-8 Sodium Azide (Na(N3)) a 1,000 500

124-65-2 Sodium Cacodylate 100 100/10,000

143-33-9 Sodium Cyanide (Na(CN)) a 10 100

62-74-8 Sodium Fluoroacetate 10 10/10,000

13410-01-0 Sodium Selenate 100 100/10,000

10102-18-8 Sodium Selenite d 100 100/10,000

10102-20-2 Sodium Tellurite 500 500/10,000

900-95-8 Stannane, Acetoxytriphenyl- c 500 500/10,000

57-24-9 Strychnine b 10 100/10,000

60-41-3 Strychnine Sulfate 10 100/10,000

3689-24-5 Sulfotep 100 500

3569-57-1 Sulfoxide, 3-Chloropropyl Octyl 500 500

7446-09-5 Sulfur Dioxide f 500 500

7783-60-0 Sulfur Tetrafluoride 100 100

7446-11-9 Sulfur Trioxide a 100 100

7664-93-9 Sulfuric Acid 1,000 1,000

77-81-6 Tabun b, d 10 10

7783-80-4 Tellurium Hexafluoride e 100 100

107-49-3 TEPP 10 100

13071-79-9 Terbufos d 100 100

78-00-2 Tetraethyllead b 10 100

597-64-8 Tetraethyltin b 100 100

75-74-1 Tetramethyllead b, f 100 100

509-14-8 Tetranitromethane 10 500

10031-59-1 Thallium Sulfate d 100 100/10,000

6533-73-9 Thallous Carbonate b, d 100 100/10,000

7791-12-0 Thallous Chloride b, d 100 100/10,000

2757-18-8 Thallous Malonate b, d 100 100/10,000

7446-18-6 Thallous Sulfate 100 100/10,000

2231-57-4 Thiocarbazide 1,000 1,000/10,000

39196-18-4 Thiofanox 100 100/10,000

297-97-2 Thionazin 100 500

108-98-5 Thiophenol 100 500

79-19-6 Thiosemicarbazide 100 100/10,000

5344-82-1 Thiourea, (2-Chlorophenyl)- 100 100/10,000

614-78-8 Thiourea, (2-Methylphenyl)- 500 500/10,000

7550-45-0 Titanium Tetrachloride 1,000 100

584-84-9 Toluene 2,4-Diisocyanate 100 500

91-08-7 Toluene 2,6-Diisocyanate 100 100

110-57-6 Trans-1,4-Dichlorobutene 500 500

1031-47-6 Triamiphos 500 500/10,000

24017-47-8 Triazofos 500 500

76-02-8 Trichloroacetyl Chloride 500 500

115-21-9 Trichloroethylsilane d 500 500

327-98-0 Trichloronate e 500 500

98-13-5 Trichlorophenylsilane d 500 500

1558-25-4 Trichloro(Chloromethyl)Silane 100 100

27137-85-5 Trichloro(Dichlorophenyl) Silane 500 500

998-30-1 Triethoxysilane 500 500

75-77-4 Trimethylchlorosilane 1,000 1,000

824-11-3 Trimethylolpropane Phosphite d 100 100/10,000

1066-45-1 Trimethyltin Chloride 500 500/10,000

639-58-7 Triphenyltin Chloride 500 500/10,000

555-77-1 Tris(2-Chloroethyl)Amine d 100 100

2001-95-8 Valinomycin b 1,000 1,000/10,000

1314-62-1 Vanadium Pentoxide 1,000 100/10,000

108-05-4 Vinyl Acetate Monomer f 5,000 1,000

81-81-2 Warfarin 100 500/10,000

129-06-6 Warfarin Sodium d 100 100/10,000

28347-13-9 Xylylene Dichloride 100 100/10,000

58270-08-9 Zinc, Dichloro(4,4-Dimethyl-5((((Methylamino)Carbonyl) Oxy)Imino)Pentanenitrile)-, (T-4)- 100 100/10,000

1314-84-7 Zinc Phosphide a 100 500

* Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.

Notes:

a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non-powder, non-molten, non-solution form.

b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.

c. Chemicals added by final rule, April 22, 1987.

d. Revised TPQ based on new or re-evaluated toxicity data, April 22, 1987.

e. The TPQ was revised due to calculation error, April 22, 1987.

f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”), November 17, 1986 and February 15, 1990.

g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987 final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.

Collected 2026-08-27T02:26:04Z. Source file · JSON

Browse this collection