Federal regulations · Through 2026-08-25 · Newer source version available

40 CFR Appendix B to Part 355: Appendix B to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities

[CAS Number Order]
CAS No. Chemical name Notes Reportable quantity * (pounds) Threshold planning quantity (pounds)
0 Organorhodium Complex (PMN-82-147) 10 10/10,000
50-00-0 Formaldehyde f 100 500
50-07-7 Mitomycin C 10 500/10,000
50-14-6 Ergocalciferol b 1,000 1,000/10,000
51-21-8 Fluorouracil 500 500/10,000
51-75-2 Mechlorethamine b 10 10
51-83-2 Carbachol Chloride 500 500/10,000
54-11-5 Nicotine b 100 100
54-62-6 Aminopterin 500 500/10,000
55-91-4 Isofluorphate b 100 100
56-25-7 Cantharidin 100 100/10,000
56-38-2 Parathion b 10 100
56-72-4 Coumaphos 10 100/10,000
57-14-7 Dimethylhydrazine 10 1,000
57-24-9 Strychnine b 10 100/10,000
57-47-6 Physostigmine 100 100/10,000
57-57-8 Propiolactone, Beta- 10 500
57-64-7 Physostigmine, Salicylate (1:1) 100 100/10,000
57-74-9 Chlordane 1 1,000
58-36-6 Phenoxarsine, 10,10′-Oxydi- 500 500/10,000
58-89-9 Lindane 1 1,000/10,000
59-88-1 Phenylhydrazine Hydrochloride 1,000 1,000/10,000
60-34-4 Methyl Hydrazine 10 500
60-41-3 Strychnine sulfate 10 100/10,000
60-51-5 Dimethoate 10 500/10,000
62-38-4 Phenylmercury Acetate 100 500/10,000
62-53-3 Aniline f 5,000 1,000
62-73-7 Dichlorvos 10 1,000
62-74-8 Sodium Fluoroacetate 10 10/10,000
62-75-9 Nitrosodimethylamine d 10 1,000
64-00-6 Phenol, 3-(1-Methylethyl)-, Methylcarbamate 10 500/10,000
64-86-8 Colchicine d 10 10/10,000
65-30-5 Nicotine sulfate 100 100/10,000
66-81-9 Cycloheximide 100 100/10,000
67-66-3 Chloroform f 10 10,000
70-69-9 Propiophenone, 4-Amino- c 100 100/10,000
71-63-6 Digitoxin b 100 100/10,000
72-20-8 Endrin 1 500/10,000
74-83-9 Methyl Bromide f 1,000 1,000
74-90-8 Hydrocyanic Acid 10 100
74-93-1 Methyl Mercaptan f 100 500
75-15-0 Carbon Disulfide f 100 10,000
75-21-8 Ethylene Oxide f 10 1,000
75-44-5 Phosgene f 10 10
75-55-8 Propyleneimine 1 10,000
75-56-9 Propylene Oxide f 100 10,000
75-74-1 Tetramethyllead b, f 100 100
75-77-4 Trimethylchlorosilane 1,000 1,000
75-78-5 Dimethyldichlorosilane d 500 500
75-79-6 Methyltrichlorosilane d 500 500
75-86-5 Acetone Cyanohydrin 10 1,000
76-02-8 Trichloroacetyl Chloride 500 500
77-47-4 Hexachlorocyclopentadiene d 10 100
77-78-1 Dimethyl Sulfate 100 500
77-81-6 Tabun b, d 10 10
78-00-2 Tetraethyllead b 10 100
78-34-2 Dioxathion 500 500
78-53-5 Amiton 500 500
78-71-7 Oxetane, 3,3-Bis(Chloromethyl)- 500 500
78-82-0 Isobutyronitrile d 1,000 1,000
78-94-4 Methyl Vinyl Ketone 10 10
78-97-7 Lactonitrile 1,000 1,000
79-06-1 Acrylamide f 5,000 1,000/10,000
79-11-8 Chloroacetic Acid 100 100/10,000
79-19-6 Thiosemicarbazide 100 100/10,000
79-21-0 Peracetic Acid 500 500
79-22-1 Methyl Chloroformate d 1,000 500
80-63-7 Methyl 2-Chloroacrylate 500 500
81-81-2 Warfarin 100 500/10,000
82-66-6 Diphacinone 10 10/10,000
86-50-0 Azinphos-Methyl 1 10/10,000
86-88-4 ANTU 100 500/10,000
88-05-1 Aniline, 2,4,6-Trimethyl- 500 500
88-85-7 Dinoseb 1,000 100/10,000
91-08-7 Toluene 2,6-Diisocyanate 100 100
95-48-7 Cresol, o- 100 1,000/10,000
98-05-5 Benzenearsonic Acid 10 10/10,000
98-07-7 Benzotrichloride 10 100
98-13-5 Trichlorophenylsilane d 500 500
98-16-8 Benzenamine, 3-(Trifluoromethyl)- 500 500
98-87-3 Benzal Chloride 5,000 500
98-95-3 Nitrobenzene f 1,000 10,000
99-98-9 Dimethyl-p-Phenylenediamine 10 10/10,000
100-14-1 Benzene, 1-(Chloromethyl)-4-Nitro- 500 500/10,000
100-44-7 Benzyl Chloride 100 500
102-36-3 Isocyanic Acid, 3,4-Dichlorophenyl Ester 500 500/10,000
103-85-5 Phenylthiourea 100 100/10,000
106-89-8 Epichlorohydrin f 100 1,000
106-96-7 Propargyl Bromide 10 10
107-02-8 Acrolein 1 500
107-07-3 Chloroethanol 500 500
107-11-9 Allylamine 500 500
107-12-0 Propionitrile 10 500
107-13-1 Acrylonitrile f 100 10,000
107-15-3 Ethylenediamine 5,000 10,000
107-16-4 Formaldehyde Cyanohydrin d 1,000 1,000
107-18-6 Allyl Alcohol 100 1,000
107-30-2 Chloromethyl Methyl Ether b 10 100
107-44-8 Sarin d 10 10
107-49-3 TEPP 10 100
108-05-4 Vinyl Acetate Monomer f 5,000 1,000
108-23-6 Isopropyl Chloroformate 1,000 1,000
108-91-8 Cyclohexylamine f 10,000 10,000
108-95-2 Phenol 1,000 500/10,000
108-98-5 Thiophenol 100 500
109-61-5 Propyl Chloroformate 500 500
109-77-3 Malononitrile 1,000 500/10,000
110-00-9 Furan 100 500
110-57-6 Trans-1,4-Dichlorobutene 500 500
110-89-4 Piperidine 1,000 1,000
111-44-4 Dichloroethyl Ether 10 10,000
111-69-3 Adiponitrile f 1,000 1,000
115-21-9 Trichloroethylsilane d 500 500
115-26-4 Dimefox 500 500
115-29-7 Endosulfan 1 10/10,000
115-90-2 Fensulfothion d 500 500
116-06-3 Aldicarb b 1 100/10,000
119-38-0 Isopropylmethyl-pyrazolyl Dimethylcarbamate 100 500
123-31-9 Hydroquinone f 100 500/10,000
123-73-9 Crotonaldehyde, (E)- 100 1,000
124-65-2 Sodium Cacodylate 100 100/10,000
124-87-8 Picrotoxin 500 500/10,000
126-98-7 Methacrylonitrile d 1,000 500
129-00-0 Pyrene b 5,000 1,000/10,000
129-06-6 Warfarin Sodium d 100 100/10,000
140-29-4 Benzyl Cyanide d 500 500
140-76-1 Pyridine, 2-Methyl-5-Vinyl- 500 500
141-66-2 Dicrotophos 100 100
143-33-9 Sodium Cyanide (Na(CN)) a 10 100
144-49-0 Fluoroacetic Acid 10 10/10,000
149-74-6 Dichloromethylphenylsilane 1,000 1,000
151-38-2 Methoxyethylmercuric Acetate 500 500/10,000
151-50-8 Potassium Cyanide a 10 100
151-56-4 Ethyleneimine 1 500
152-16-9 Diphosphoramide, Octamethyl- 100 100
297-78-9 Isobenzan 100 100/10,000
297-97-2 Thionazin 100 500
298-00-0 Parathion-Methyl b 100 100/10,000
298-02-2 Phorate 10 10
298-04-4 Disulfoton 1 500
300-62-9 Amphetamine 1,000 1,000
302-01-2 Hydrazine 1 1,000
309-00-2 Aldrin 1 500/10,000
315-18-4 Mexacarbate 1,000 500/10,000
316-42-7 Emetine, Dihydrochloride d 1 1/10,000
327-98-0 Trichloronate e 500 500
353-42-4 Boron Trifluoride Compound With Methyl Ether (1:1) 1,000 1,000
359-06-8 Fluoroacetyl Chloride b 10 10
371-62-0 Ethylene Fluorohydrin b, d 10 10
379-79-3 Ergotamine Tartrate 500 500/10,000
465-73-6 Isodrin 1 100/10,000
470-90-6 Chlorfenvinfos 500 500
502-39-6 Methylmercuric Dicyanamide 500 500/10,000
504-24-5 Pyridine, 4-Amino- d 1,000 500/10,000
505-60-2 Mustard Gas d 500 500
506-61-6 Potassium Silver Cyanide a 1 500
506-68-3 Cyanogen Bromide 1,000 500/10,000
506-78-5 Cyanogen Iodide 1,000 1,000/10,000
509-14-8 Tetranitromethane 10 500
514-73-8 Dithiazanine Iodide 500 500/10,000
534-07-6 Bis(Chloromethyl) Ketone 10 10/10,000
534-52-1 Dinitrocresol 10 10/10,000
535-89-7 Crimidine 100 100/10,000
538-07-8 Ethylbis(2-Chloroethyl)Amine d 500 500
541-25-3 Lewisite b, d 10 10
541-53-7 Dithiobiuret 100 100/10,000
542-76-7 Propionitrile, 3-Chloro- 1,000 1,000
542-88-1 Chloromethyl Ether d 10 100
542-90-5 Ethylthiocyanate 10,000 10,000
555-77-1 Tris(2-Chloroethyl)Amine d 100 100
556-61-6 Methyl Isothiocyanate a 500 500
556-64-9 Methyl Thiocyanate 10,000 10,000
558-25-8 Methanesulfonyl Fluoride 1,000 1,000
563-12-2 Ethion 10 1,000
563-41-7 Semicarbazide Hydrochloride 1,000 1,000/10,000
584-84-9 Toluene 2,4-Diisocyanate 100 500
594-42-3 Perchloromethylmercaptan 100 500
597-64-8 Tetraethyltin b 100 100
614-78-8 Thiourea, (2-Methylphenyl)- 500 500/10,000
624-83-9 Methyl Isocyanate 10 500
627-11-2 Chloroethyl Chloroformate 1,000 1,000
630-60-4 Ouabain b 100 100/10,000
639-58-7 Triphenyltin Chloride 500 500/10,000
640-19-7 Fluoroacetamide 100 100/10,000
644-64-4 Dimetilan 1 500/10,000
675-14-9 Cyanuric Fluoride 100 100
676-97-1 Methyl Phosphonic Dichloride a 100 100
696-28-6 Phenyl Dichloroarsine d 1 500
760-93-0 Methacrylic Anhydride 500 500
786-19-6 Carbophenothion 500 500
814-49-3 Diethyl Chlorophosphate d 500 500
814-68-6 Acrylyl Chloride d 100 100
824-11-3 Trimethylolpropane Phosphite d 100 100/10,000
900-95-8 Stannane, Acetoxytriphenyl- c 500 500/10,000
919-86-8 Demeton-S-Methyl 500 500
920-46-7 Methacryloyl Chloride 100 100
944-22-9 Fonofos 500 500
947-02-4 Phosfolan 100 100/10,000
950-10-7 Mephosfolan 500 500
950-37-8 Methidathion 500 500/10,000
991-42-4 Norbormide 100 100/10,000
998-30-1 Triethoxysilane 500 500
999-81-5 Chlormequat Chloride d 100 100/10,000
1031-47-6 Triamiphos 500 500/10,000
1066-45-1 Trimethyltin Chloride 500 500/10,000
1122-60-7 Nitrocyclohexane 500 500
1124-33-0 Pyridine, 4-Nitro-,1-Oxide 500 500/10,000
1129-41-5 Metolcarb 1,000 100/10,000
1303-28-2 Arsenic Pentoxide 1 100/10,000
1306-19-0 Cadmium Oxide 100 100/10,000
1314-62-1 Vanadium Pentoxide 1,000 100/10,000
1314-84-7 Zinc Phosphide a 100 500
1327-53-3 Arsenous Oxide d 1 100/10,000
1397-94-0 Antimycin A b 1,000 1,000/10,000
1420-07-1 Dinoterb 500 500/10,000
1464-53-5 Diepoxybutane 10 500
1558-25-4 Trichloro(Chloromethyl)Silane 100 100
1563-66-2 Carbofuran 10 10/10,000
1600-27-7 Mercuric Acetate 500 500/10,000
1622-32-8 Ethanesulfonyl Chloride, 2-Chloro- 500 500
1752-30-3 Acetone Thiosemicarbazide 1,000 1,000/10,000
1910-42-5 Paraquat Dichloride 10 10/10,000
1982-47-4 Chloroxuron 500 500/10,000
2001-95-8 Valinomycin b 1,000 1,000/10,000
2032-65-7 Methiocarb 10 500/10,000
2074-50-2 Paraquat Methosulfate 10 10/10,000
2097-19-0 Phenylsilatrane d 100 100/10,000
2104-64-5 EPN 100 100/10,000
2223-93-0 Cadmium Stearate b 1,000 1,000/10,000
2231-57-4 Thiocarbazide 1,000 1,000/10,000
2238-07-5 Diglycidyl Ether 1,000 1,000
2275-18-5 Prothoate 100 100/10,000
2497-07-6 Oxydisulfoton d 500 500
2524-03-0 Dimethyl Phosphorochloridothioate 500 500
2540-82-1 Formothion 100 100
2570-26-5 Pentadecylamine 100 100/10,000
2587-90-8 Phosphorothioic Acid, O,O-Dimethyl-S-(2-Methylthio) Ethyl Ester b, c 500 500
2631-37-0 Promecarb d 1,000 500/10,000
2636-26-2 Cyanophos 1,000 1,000
2642-71-9 Azinphos-Ethyl 100 100/10,000
2665-30-7 Phosphonothioic Acid, Methyl-, O-(4-Nitrophenyl) O-Phenyl Ester 500 500
2703-13-1 Phosphonothioic Acid, Methyl-, O-Ethyl O-(4-(Methylthio)Phenyl) Ester 500 500
2757-18-8 Thallous Malonate b, d 100 100/10,000
2763-96-4 Muscimol 1,000 500/10,000
2778-04-3 Endothion 500 500/10,000
3037-72-7 Silane, (4-Aminobutyl)Diethoxymethyl- 1,000 1,000
3254-63-5 Phosphoric Acid, Dimethyl 4-(Methylthio)Phenyl Ester 500 500
3569-57-1 Sulfoxide, 3-Chloropropyl Octyl 500 500
3615-21-2 Benzimidazole, 4,5-Dichloro-2-(Trifluoromethyl)- c 500 500/10,000
3689-24-5 Sulfotep 100 500
3691-35-8 Chlorophacinone 100 100/10,000
3734-97-2 Amiton Oxalate 100 100/10,000
3735-23-7 Methyl Phenkapton 500 500
3878-19-1 Fuberidazole 100 100/10,000
4044-65-9 Bitoscanate 500 500/10,000
4098-71-9 Isophorone Diisocyanate g 500 500
4104-14-7 Phosacetim 100 100/10,000
4170-30-3 Crotonaldehyde 100 1,000
4301-50-2 Fluenetil 100 100/10,000
4418-66-0 Phenol, 2,2′-Thiobis(4-Chloro-6-Methyl)- 100 100/10,000
4835-11-4 Hexamethylenediamine, N,N′-Dibutyl- 500 500
5344-82-1 Thiourea, (2-Chlorophenyl)- 100 100/10,000
5836-29-3 Coumatetralyl 500 500/10,000
6533-73-9 Thallous Carbonate b, d 100 100/10,000
6923-22-4 Monocrotophos 10 10/10,000
7446-09-5 Sulfur Dioxide f 500 500
7446-11-9 Sulfur Trioxide a 100 100
7446-18-6 Thallous Sulfate 100 100/10,000
7487-94-7 Mercuric Chloride 500 500/10,000
7550-45-0 Titanium Tetrachloride 1,000 100
7580-67-8 Lithium Hydride a 100 100
7631-89-2 Sodium Arsenate 1 1,000/10,000
7637-07-2 Boron Trifluoride 500 500
7647-01-0 Hydrogen Chloride (gas only) f 5,000 500
7664-39-3 Hydrogen Fluoride 100 100
7664-41-7 Ammonia f 100 500
7664-93-9 Sulfuric Acid 1,000 1,000
7697-37-2 Nitric Acid 1,000 1,000
7719-12-2 Phosphorus Trichloride 1,000 1,000
7722-84-1 Hydrogen Peroxide (Conc >52%) f 1,000 1,000
7723-14-0 Phosphorus a, d 1 100
7726-95-6 Bromine f 500 500
7778-44-1 Calcium Arsenate 1 500/10,000
7782-41-4 Fluorine e 10 500
7782-50-5 Chlorine 10 100
7783-00-8 Selenious Acid 10 1,000/10,000
7783-06-4 Hydrogen Sulfide f 100 500
7783-07-5 Hydrogen Selenide 10 10
7783-60-0 Sulfur Tetrafluoride 100 100
7783-70-2 Antimony Pentafluoride 500 500
7783-80-4 Tellurium Hexafluoride e 100 100
7784-34-1 Arsenous Trichloride 1 500
7784-42-1 Arsine 100 100
7784-46-5 Sodium Arsenite 1 500/10,000
7786-34-7 Mevinphos 10 500
7791-12-0 Thallous Chloride b, d 100 100/10,000
7791-23-3 Selenium Oxychloride 500 500
7803-51-2 Phosphine 100 500
8001-35-2 Camphechlor 1 500/10,000
8065-48-3 Demeton 500 500
10025-73-7 Chromic Chloride 1 1/10,000
10025-87-3 Phosphorus Oxychloride 1,000 500
10026-13-8 Phosphorus Pentachloride a 500 500
10028-15-6 Ozone 100 100
10031-59-1 Thallium Sulfate d 100 100/10,000
10102-18-8 Sodium Selenite d 100 100/10,000
10102-20-2 Sodium Tellurite 500 500/10,000
10102-43-9 Nitric Oxide b 10 100
10102-44-0 Nitrogen Dioxide 10 100
10124-50-2 Potassium Arsenite 1 500/10,000
10140-87-1 Ethanol, 1,2-Dichloro-, Acetate 1,000 1,000
10210-68-1 Cobalt Carbonyl d 10 10/10,000
10265-92-6 Methamidophos 100 100/10,000
10294-34-5 Boron Trichloride 500 500
10311-84-9 Dialifor 100 100/10,000
10476-95-6 Methacrolein Diacetate 1,000 1,000
12002-03-8 Paris Green 1 500/10,000
12108-13-3 Manganese, Tricarbonyl Methylcyclopentadienyl d 100 100
13071-79-9 Terbufosh d 100 100
13171-21-6 Phosphamidon 100 100
13194-48-4 Ethoprophos 1,000 1,000
13410-01-0 Sodium Selenate 100 100/10,000
13450-90-3 Gallium Trichloride 500 500/10,000
13463-39-3 Nickel Carbonyl 10 1
13463-40-6 Iron, Pentacarbonyl- 100 100
14167-18-1 Salcomine 500 500/10,000
15271-41-7 Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Chloro-6-((((Methylamino)Carbonyl)Oxy)Imino)-, (1s-(1-alpha,2-beta,4-alpha,5-alpha,6E))- 500 500/10,000
16752-77-5 Methomyl d 100 500/10,000
17702-41-9 Decaborane(14) 500 500/10,000
17702-57-7 Formparanate 100 100/10,000
19287-45-7 Diborane 100 100
19624-22-7 Pentaborane 500 500
20830-75-5 Digoxin d 10 10/10,000
20859-73-8 Aluminum Phosphide a 100 500
21548-32-3 Fosthietan 500 500
21609-90-5 Leptophos 500 500/10,000
21908-53-2 Mercuric Oxide 500 500/10,000
21923-23-9 Chlorthiophos d 500 500
22224-92-6 Fenamiphos 10 10/10,000
23135-22-0 Oxamyl 100 100/10,000
23422-53-9 Formetanate Hydrochloride d 100 500/10,000
23505-41-1 Pirimifos-Ethyl 1,000 1,000
24017-47-8 Triazofos 500 500
24934-91-6 Chlormephos 500 500
26419-73-8 Carbamic Acid, Methyl-, O-(((2,4-Dimethyl-1, 3-Dithiolan-2-yl)Methylene)Amino)- 100 100/10,000
26628-22-8 Sodium Azide (Na(N3)) a 1,000 500
27137-85-5 Trichloro(Dichlorophenyl)Silane 500 500
28347-13-9 Xylylene Dichloride 100 100/10,000
28772-56-7 Bromadiolone 100 100/10,000
30674-80-7 Methacryloyloxyethyl Isocyanateh 100 100
39196-18-4 Thiofanox 100 100/10,000
50782-69-9 Phosphonothioic Acid, Methyl-, S-(2-(Bis(1-Methylethyl)Amino)Ethyl) O-Ethyl Ester 100 100
53558-25-1 Pyriminil d 100 100/10,000
58270-08-9 Zinc, Dichloro(4,4-Dimethyl-5((((Methylamino) Carbonyl)Oxy)Imino)Pentanenitrile)-, (T-4)- 100 100/10,000
62207-76-5 Cobalt, ((2,2′-(1,2-Ethanediylbis (Nitrilomethylidyne)) Bis(6-Fluorophenolato)) (2-)-N,N′,O,O′)- 100 100/10,000
* Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.
Notes:
a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non-powder, non-molten, non-solution form.
b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.
c. Chemicals added by final rule, April 22, 1987.
d. Revised TPQ based on new or re-evaluated toxicity data, April 22, 1987.
e. The TPQ was revised due to calculation error, April 22, 1987.
f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”). (November 17, 1986, and February 15, 1990.)
g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987, final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.

Where this section sits in the code

Title 40—Protection of Environment
CHAPTER I—ENVIRONMENTAL PROTECTION AGENCY
SUBCHAPTER J—SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS
PART 355—EMERGENCY PLANNING AND NOTIFICATION

[CAS Number Order]

CAS No. Chemical name Notes Reportable quantity * (pounds) Threshold planning quantity (pounds)

0 Organorhodium Complex (PMN-82-147) 10 10/10,000

50-00-0 Formaldehyde f 100 500

50-07-7 Mitomycin C 10 500/10,000

50-14-6 Ergocalciferol b 1,000 1,000/10,000

51-21-8 Fluorouracil 500 500/10,000

51-75-2 Mechlorethamine b 10 10

51-83-2 Carbachol Chloride 500 500/10,000

54-11-5 Nicotine b 100 100

54-62-6 Aminopterin 500 500/10,000

55-91-4 Isofluorphate b 100 100

56-25-7 Cantharidin 100 100/10,000

56-38-2 Parathion b 10 100

56-72-4 Coumaphos 10 100/10,000

57-14-7 Dimethylhydrazine 10 1,000

57-24-9 Strychnine b 10 100/10,000

57-47-6 Physostigmine 100 100/10,000

57-57-8 Propiolactone, Beta- 10 500

57-64-7 Physostigmine, Salicylate (1:1) 100 100/10,000

57-74-9 Chlordane 1 1,000

58-36-6 Phenoxarsine, 10,10′-Oxydi- 500 500/10,000

58-89-9 Lindane 1 1,000/10,000

59-88-1 Phenylhydrazine Hydrochloride 1,000 1,000/10,000

60-34-4 Methyl Hydrazine 10 500

60-41-3 Strychnine sulfate 10 100/10,000

60-51-5 Dimethoate 10 500/10,000

62-38-4 Phenylmercury Acetate 100 500/10,000

62-53-3 Aniline f 5,000 1,000

62-73-7 Dichlorvos 10 1,000

62-74-8 Sodium Fluoroacetate 10 10/10,000

62-75-9 Nitrosodimethylamine d 10 1,000

64-00-6 Phenol, 3-(1-Methylethyl)-, Methylcarbamate 10 500/10,000

64-86-8 Colchicine d 10 10/10,000

65-30-5 Nicotine sulfate 100 100/10,000

66-81-9 Cycloheximide 100 100/10,000

67-66-3 Chloroform f 10 10,000

70-69-9 Propiophenone, 4-Amino- c 100 100/10,000

71-63-6 Digitoxin b 100 100/10,000

72-20-8 Endrin 1 500/10,000

74-83-9 Methyl Bromide f 1,000 1,000

74-90-8 Hydrocyanic Acid 10 100

74-93-1 Methyl Mercaptan f 100 500

75-15-0 Carbon Disulfide f 100 10,000

75-21-8 Ethylene Oxide f 10 1,000

75-44-5 Phosgene f 10 10

75-55-8 Propyleneimine 1 10,000

75-56-9 Propylene Oxide f 100 10,000

75-74-1 Tetramethyllead b, f 100 100

75-77-4 Trimethylchlorosilane 1,000 1,000

75-78-5 Dimethyldichlorosilane d 500 500

75-79-6 Methyltrichlorosilane d 500 500

75-86-5 Acetone Cyanohydrin 10 1,000

76-02-8 Trichloroacetyl Chloride 500 500

77-47-4 Hexachlorocyclopentadiene d 10 100

77-78-1 Dimethyl Sulfate 100 500

77-81-6 Tabun b, d 10 10

78-00-2 Tetraethyllead b 10 100

78-34-2 Dioxathion 500 500

78-53-5 Amiton 500 500

78-71-7 Oxetane, 3,3-Bis(Chloromethyl)- 500 500

78-82-0 Isobutyronitrile d 1,000 1,000

78-94-4 Methyl Vinyl Ketone 10 10

78-97-7 Lactonitrile 1,000 1,000

79-06-1 Acrylamide f 5,000 1,000/10,000

79-11-8 Chloroacetic Acid 100 100/10,000

79-19-6 Thiosemicarbazide 100 100/10,000

79-21-0 Peracetic Acid 500 500

79-22-1 Methyl Chloroformate d 1,000 500

80-63-7 Methyl 2-Chloroacrylate 500 500

81-81-2 Warfarin 100 500/10,000

82-66-6 Diphacinone 10 10/10,000

86-50-0 Azinphos-Methyl 1 10/10,000

86-88-4 ANTU 100 500/10,000

88-05-1 Aniline, 2,4,6-Trimethyl- 500 500

88-85-7 Dinoseb 1,000 100/10,000

91-08-7 Toluene 2,6-Diisocyanate 100 100

95-48-7 Cresol, o- 100 1,000/10,000

98-05-5 Benzenearsonic Acid 10 10/10,000

98-07-7 Benzotrichloride 10 100

98-13-5 Trichlorophenylsilane d 500 500

98-16-8 Benzenamine, 3-(Trifluoromethyl)- 500 500

98-87-3 Benzal Chloride 5,000 500

98-95-3 Nitrobenzene f 1,000 10,000

99-98-9 Dimethyl-p-Phenylenediamine 10 10/10,000

100-14-1 Benzene, 1-(Chloromethyl)-4-Nitro- 500 500/10,000

100-44-7 Benzyl Chloride 100 500

102-36-3 Isocyanic Acid, 3,4-Dichlorophenyl Ester 500 500/10,000

103-85-5 Phenylthiourea 100 100/10,000

106-89-8 Epichlorohydrin f 100 1,000

106-96-7 Propargyl Bromide 10 10

107-02-8 Acrolein 1 500

107-07-3 Chloroethanol 500 500

107-11-9 Allylamine 500 500

107-12-0 Propionitrile 10 500

107-13-1 Acrylonitrile f 100 10,000

107-15-3 Ethylenediamine 5,000 10,000

107-16-4 Formaldehyde Cyanohydrin d 1,000 1,000

107-18-6 Allyl Alcohol 100 1,000

107-30-2 Chloromethyl Methyl Ether b 10 100

107-44-8 Sarin d 10 10

107-49-3 TEPP 10 100

108-05-4 Vinyl Acetate Monomer f 5,000 1,000

108-23-6 Isopropyl Chloroformate 1,000 1,000

108-91-8 Cyclohexylamine f 10,000 10,000

108-95-2 Phenol 1,000 500/10,000

108-98-5 Thiophenol 100 500

109-61-5 Propyl Chloroformate 500 500

109-77-3 Malononitrile 1,000 500/10,000

110-00-9 Furan 100 500

110-57-6 Trans-1,4-Dichlorobutene 500 500

110-89-4 Piperidine 1,000 1,000

111-44-4 Dichloroethyl Ether 10 10,000

111-69-3 Adiponitrile f 1,000 1,000

115-21-9 Trichloroethylsilane d 500 500

115-26-4 Dimefox 500 500

115-29-7 Endosulfan 1 10/10,000

115-90-2 Fensulfothion d 500 500

116-06-3 Aldicarb b 1 100/10,000

119-38-0 Isopropylmethyl-pyrazolyl Dimethylcarbamate 100 500

123-31-9 Hydroquinone f 100 500/10,000

123-73-9 Crotonaldehyde, (E)- 100 1,000

124-65-2 Sodium Cacodylate 100 100/10,000

124-87-8 Picrotoxin 500 500/10,000

126-98-7 Methacrylonitrile d 1,000 500

129-00-0 Pyrene b 5,000 1,000/10,000

129-06-6 Warfarin Sodium d 100 100/10,000

140-29-4 Benzyl Cyanide d 500 500

140-76-1 Pyridine, 2-Methyl-5-Vinyl- 500 500

141-66-2 Dicrotophos 100 100

143-33-9 Sodium Cyanide (Na(CN)) a 10 100

144-49-0 Fluoroacetic Acid 10 10/10,000

149-74-6 Dichloromethylphenylsilane 1,000 1,000

151-38-2 Methoxyethylmercuric Acetate 500 500/10,000

151-50-8 Potassium Cyanide a 10 100

151-56-4 Ethyleneimine 1 500

152-16-9 Diphosphoramide, Octamethyl- 100 100

297-78-9 Isobenzan 100 100/10,000

297-97-2 Thionazin 100 500

298-00-0 Parathion-Methyl b 100 100/10,000

298-02-2 Phorate 10 10

298-04-4 Disulfoton 1 500

300-62-9 Amphetamine 1,000 1,000

302-01-2 Hydrazine 1 1,000

309-00-2 Aldrin 1 500/10,000

315-18-4 Mexacarbate 1,000 500/10,000

316-42-7 Emetine, Dihydrochloride d 1 1/10,000

327-98-0 Trichloronate e 500 500

353-42-4 Boron Trifluoride Compound With Methyl Ether (1:1) 1,000 1,000

359-06-8 Fluoroacetyl Chloride b 10 10

371-62-0 Ethylene Fluorohydrin b, d 10 10

379-79-3 Ergotamine Tartrate 500 500/10,000

465-73-6 Isodrin 1 100/10,000

470-90-6 Chlorfenvinfos 500 500

502-39-6 Methylmercuric Dicyanamide 500 500/10,000

504-24-5 Pyridine, 4-Amino- d 1,000 500/10,000

505-60-2 Mustard Gas d 500 500

506-61-6 Potassium Silver Cyanide a 1 500

506-68-3 Cyanogen Bromide 1,000 500/10,000

506-78-5 Cyanogen Iodide 1,000 1,000/10,000

509-14-8 Tetranitromethane 10 500

514-73-8 Dithiazanine Iodide 500 500/10,000

534-07-6 Bis(Chloromethyl) Ketone 10 10/10,000

534-52-1 Dinitrocresol 10 10/10,000

535-89-7 Crimidine 100 100/10,000

538-07-8 Ethylbis(2-Chloroethyl)Amine d 500 500

541-25-3 Lewisite b, d 10 10

541-53-7 Dithiobiuret 100 100/10,000

542-76-7 Propionitrile, 3-Chloro- 1,000 1,000

542-88-1 Chloromethyl Ether d 10 100

542-90-5 Ethylthiocyanate 10,000 10,000

555-77-1 Tris(2-Chloroethyl)Amine d 100 100

556-61-6 Methyl Isothiocyanate a 500 500

556-64-9 Methyl Thiocyanate 10,000 10,000

558-25-8 Methanesulfonyl Fluoride 1,000 1,000

563-12-2 Ethion 10 1,000

563-41-7 Semicarbazide Hydrochloride 1,000 1,000/10,000

584-84-9 Toluene 2,4-Diisocyanate 100 500

594-42-3 Perchloromethylmercaptan 100 500

597-64-8 Tetraethyltin b 100 100

614-78-8 Thiourea, (2-Methylphenyl)- 500 500/10,000

624-83-9 Methyl Isocyanate 10 500

627-11-2 Chloroethyl Chloroformate 1,000 1,000

630-60-4 Ouabain b 100 100/10,000

639-58-7 Triphenyltin Chloride 500 500/10,000

640-19-7 Fluoroacetamide 100 100/10,000

644-64-4 Dimetilan 1 500/10,000

675-14-9 Cyanuric Fluoride 100 100

676-97-1 Methyl Phosphonic Dichloride a 100 100

696-28-6 Phenyl Dichloroarsine d 1 500

760-93-0 Methacrylic Anhydride 500 500

786-19-6 Carbophenothion 500 500

814-49-3 Diethyl Chlorophosphate d 500 500

814-68-6 Acrylyl Chloride d 100 100

824-11-3 Trimethylolpropane Phosphite d 100 100/10,000

900-95-8 Stannane, Acetoxytriphenyl- c 500 500/10,000

919-86-8 Demeton-S-Methyl 500 500

920-46-7 Methacryloyl Chloride 100 100

944-22-9 Fonofos 500 500

947-02-4 Phosfolan 100 100/10,000

950-10-7 Mephosfolan 500 500

950-37-8 Methidathion 500 500/10,000

991-42-4 Norbormide 100 100/10,000

998-30-1 Triethoxysilane 500 500

999-81-5 Chlormequat Chloride d 100 100/10,000

1031-47-6 Triamiphos 500 500/10,000

1066-45-1 Trimethyltin Chloride 500 500/10,000

1122-60-7 Nitrocyclohexane 500 500

1124-33-0 Pyridine, 4-Nitro-,1-Oxide 500 500/10,000

1129-41-5 Metolcarb 1,000 100/10,000

1303-28-2 Arsenic Pentoxide 1 100/10,000

1306-19-0 Cadmium Oxide 100 100/10,000

1314-62-1 Vanadium Pentoxide 1,000 100/10,000

1314-84-7 Zinc Phosphide a 100 500

1327-53-3 Arsenous Oxide d 1 100/10,000

1397-94-0 Antimycin A b 1,000 1,000/10,000

1420-07-1 Dinoterb 500 500/10,000

1464-53-5 Diepoxybutane 10 500

1558-25-4 Trichloro(Chloromethyl)Silane 100 100

1563-66-2 Carbofuran 10 10/10,000

1600-27-7 Mercuric Acetate 500 500/10,000

1622-32-8 Ethanesulfonyl Chloride, 2-Chloro- 500 500

1752-30-3 Acetone Thiosemicarbazide 1,000 1,000/10,000

1910-42-5 Paraquat Dichloride 10 10/10,000

1982-47-4 Chloroxuron 500 500/10,000

2001-95-8 Valinomycin b 1,000 1,000/10,000

2032-65-7 Methiocarb 10 500/10,000

2074-50-2 Paraquat Methosulfate 10 10/10,000

2097-19-0 Phenylsilatrane d 100 100/10,000

2104-64-5 EPN 100 100/10,000

2223-93-0 Cadmium Stearate b 1,000 1,000/10,000

2231-57-4 Thiocarbazide 1,000 1,000/10,000

2238-07-5 Diglycidyl Ether 1,000 1,000

2275-18-5 Prothoate 100 100/10,000

2497-07-6 Oxydisulfoton d 500 500

2524-03-0 Dimethyl Phosphorochloridothioate 500 500

2540-82-1 Formothion 100 100

2570-26-5 Pentadecylamine 100 100/10,000

2587-90-8 Phosphorothioic Acid, O,O-Dimethyl-S-(2-Methylthio) Ethyl Ester b, c 500 500

2631-37-0 Promecarb d 1,000 500/10,000

2636-26-2 Cyanophos 1,000 1,000

2642-71-9 Azinphos-Ethyl 100 100/10,000

2665-30-7 Phosphonothioic Acid, Methyl-, O-(4-Nitrophenyl) O-Phenyl Ester 500 500

2703-13-1 Phosphonothioic Acid, Methyl-, O-Ethyl O-(4-(Methylthio)Phenyl) Ester 500 500

2757-18-8 Thallous Malonate b, d 100 100/10,000

2763-96-4 Muscimol 1,000 500/10,000

2778-04-3 Endothion 500 500/10,000

3037-72-7 Silane, (4-Aminobutyl)Diethoxymethyl- 1,000 1,000

3254-63-5 Phosphoric Acid, Dimethyl 4-(Methylthio)Phenyl Ester 500 500

3569-57-1 Sulfoxide, 3-Chloropropyl Octyl 500 500

3615-21-2 Benzimidazole, 4,5-Dichloro-2-(Trifluoromethyl)- c 500 500/10,000

3689-24-5 Sulfotep 100 500

3691-35-8 Chlorophacinone 100 100/10,000

3734-97-2 Amiton Oxalate 100 100/10,000

3735-23-7 Methyl Phenkapton 500 500

3878-19-1 Fuberidazole 100 100/10,000

4044-65-9 Bitoscanate 500 500/10,000

4098-71-9 Isophorone Diisocyanate g 500 500

4104-14-7 Phosacetim 100 100/10,000

4170-30-3 Crotonaldehyde 100 1,000

4301-50-2 Fluenetil 100 100/10,000

4418-66-0 Phenol, 2,2′-Thiobis(4-Chloro-6-Methyl)- 100 100/10,000

4835-11-4 Hexamethylenediamine, N,N′-Dibutyl- 500 500

5344-82-1 Thiourea, (2-Chlorophenyl)- 100 100/10,000

5836-29-3 Coumatetralyl 500 500/10,000

6533-73-9 Thallous Carbonate b, d 100 100/10,000

6923-22-4 Monocrotophos 10 10/10,000

7446-09-5 Sulfur Dioxide f 500 500

7446-11-9 Sulfur Trioxide a 100 100

7446-18-6 Thallous Sulfate 100 100/10,000

7487-94-7 Mercuric Chloride 500 500/10,000

7550-45-0 Titanium Tetrachloride 1,000 100

7580-67-8 Lithium Hydride a 100 100

7631-89-2 Sodium Arsenate 1 1,000/10,000

7637-07-2 Boron Trifluoride 500 500

7647-01-0 Hydrogen Chloride (gas only) f 5,000 500

7664-39-3 Hydrogen Fluoride 100 100

7664-41-7 Ammonia f 100 500

7664-93-9 Sulfuric Acid 1,000 1,000

7697-37-2 Nitric Acid 1,000 1,000

7719-12-2 Phosphorus Trichloride 1,000 1,000

7722-84-1 Hydrogen Peroxide (Conc >52%) f 1,000 1,000

7723-14-0 Phosphorus a, d 1 100

7726-95-6 Bromine f 500 500

7778-44-1 Calcium Arsenate 1 500/10,000

7782-41-4 Fluorine e 10 500

7782-50-5 Chlorine 10 100

7783-00-8 Selenious Acid 10 1,000/10,000

7783-06-4 Hydrogen Sulfide f 100 500

7783-07-5 Hydrogen Selenide 10 10

7783-60-0 Sulfur Tetrafluoride 100 100

7783-70-2 Antimony Pentafluoride 500 500

7783-80-4 Tellurium Hexafluoride e 100 100

7784-34-1 Arsenous Trichloride 1 500

7784-42-1 Arsine 100 100

7784-46-5 Sodium Arsenite 1 500/10,000

7786-34-7 Mevinphos 10 500

7791-12-0 Thallous Chloride b, d 100 100/10,000

7791-23-3 Selenium Oxychloride 500 500

7803-51-2 Phosphine 100 500

8001-35-2 Camphechlor 1 500/10,000

8065-48-3 Demeton 500 500

10025-73-7 Chromic Chloride 1 1/10,000

10025-87-3 Phosphorus Oxychloride 1,000 500

10026-13-8 Phosphorus Pentachloride a 500 500

10028-15-6 Ozone 100 100

10031-59-1 Thallium Sulfate d 100 100/10,000

10102-18-8 Sodium Selenite d 100 100/10,000

10102-20-2 Sodium Tellurite 500 500/10,000

10102-43-9 Nitric Oxide b 10 100

10102-44-0 Nitrogen Dioxide 10 100

10124-50-2 Potassium Arsenite 1 500/10,000

10140-87-1 Ethanol, 1,2-Dichloro-, Acetate 1,000 1,000

10210-68-1 Cobalt Carbonyl d 10 10/10,000

10265-92-6 Methamidophos 100 100/10,000

10294-34-5 Boron Trichloride 500 500

10311-84-9 Dialifor 100 100/10,000

10476-95-6 Methacrolein Diacetate 1,000 1,000

12002-03-8 Paris Green 1 500/10,000

12108-13-3 Manganese, Tricarbonyl Methylcyclopentadienyl d 100 100

13071-79-9 Terbufosh d 100 100

13171-21-6 Phosphamidon 100 100

13194-48-4 Ethoprophos 1,000 1,000

13410-01-0 Sodium Selenate 100 100/10,000

13450-90-3 Gallium Trichloride 500 500/10,000

13463-39-3 Nickel Carbonyl 10 1

13463-40-6 Iron, Pentacarbonyl- 100 100

14167-18-1 Salcomine 500 500/10,000

15271-41-7 Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Chloro-6-((((Methylamino)Carbonyl)Oxy)Imino)-, (1s-(1-alpha,2-beta,4-alpha,5-alpha,6E))- 500 500/10,000

16752-77-5 Methomyl d 100 500/10,000

17702-41-9 Decaborane(14) 500 500/10,000

17702-57-7 Formparanate 100 100/10,000

19287-45-7 Diborane 100 100

19624-22-7 Pentaborane 500 500

20830-75-5 Digoxin d 10 10/10,000

20859-73-8 Aluminum Phosphide a 100 500

21548-32-3 Fosthietan 500 500

21609-90-5 Leptophos 500 500/10,000

21908-53-2 Mercuric Oxide 500 500/10,000

21923-23-9 Chlorthiophos d 500 500

22224-92-6 Fenamiphos 10 10/10,000

23135-22-0 Oxamyl 100 100/10,000

23422-53-9 Formetanate Hydrochloride d 100 500/10,000

23505-41-1 Pirimifos-Ethyl 1,000 1,000

24017-47-8 Triazofos 500 500

24934-91-6 Chlormephos 500 500

26419-73-8 Carbamic Acid, Methyl-, O-(((2,4-Dimethyl-1, 3-Dithiolan-2-yl)Methylene)Amino)- 100 100/10,000

26628-22-8 Sodium Azide (Na(N3)) a 1,000 500

27137-85-5 Trichloro(Dichlorophenyl)Silane 500 500

28347-13-9 Xylylene Dichloride 100 100/10,000

28772-56-7 Bromadiolone 100 100/10,000

30674-80-7 Methacryloyloxyethyl Isocyanateh 100 100

39196-18-4 Thiofanox 100 100/10,000

50782-69-9 Phosphonothioic Acid, Methyl-, S-(2-(Bis(1-Methylethyl)Amino)Ethyl) O-Ethyl Ester 100 100

53558-25-1 Pyriminil d 100 100/10,000

58270-08-9 Zinc, Dichloro(4,4-Dimethyl-5((((Methylamino) Carbonyl)Oxy)Imino)Pentanenitrile)-, (T-4)- 100 100/10,000

62207-76-5 Cobalt, ((2,2′-(1,2-Ethanediylbis (Nitrilomethylidyne)) Bis(6-Fluorophenolato)) (2-)-N,N′,O,O′)- 100 100/10,000

* Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.

Notes:

a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non-powder, non-molten, non-solution form.

b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.

c. Chemicals added by final rule, April 22, 1987.

d. Revised TPQ based on new or re-evaluated toxicity data, April 22, 1987.

e. The TPQ was revised due to calculation error, April 22, 1987.

f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”). (November 17, 1986, and February 15, 1990.)

g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987, final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.

Collected 2026-08-27T02:26:04Z. Source file · JSON

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